While week 0 has officially passed, the season officially gets underway for most of the FBS teams this weekend. So I want to talk about the games I am most interested in for this first week of the new season.
1. Clemson at No. 11 LSU (Sept. 5. 6:30 pm abc)
The Lane Kiffin era at LSU gets underway as his new team takes on Clemson in the back half of a home-and-home series between the two schools which are named the Tigers and have their stadiums nicknamed “Death Valley”. The trajectories of each team’s seasons could be determined after this one. Last season, Clemson, who was ranked No. 4 in the preseason poll lost this game and finished the year unranked. While LSU didn’t have a great end either which led to former Head Coach Brian Kelley being fired and Kiffin taking over, both Kiffin and Clemson Head Coach Dabo Swinney need a win to start this season.
2. Wisconsin at No. 4 Notre Dame (Sept. 6. 6:30 pm NBC)
A matchup that was delayed six years due to COVID-19 will finally take place. Wisconsin will hold its second ever game at Lambeau Field against the Fighting Irish. Notre Dame, after ending last year abruptly by declining a bowl bid after being declined a spot in the Playoff head into the 2026 season ranked No. 4. It’s a big game for coach Marcus Freeman as he can officially erase the sting from last year and begin this year on the right track. The team on the other side in Wisconsin and coach Luke Fickell, this is a big prove it year for him. After back to back seasons of missing a bowl game in years with tough schedules and QB issues; Fickell not only found a good QB in the Portal in Colton Joseph, he has an easier schedule to have to navigate in 2026. This start is also a good opportunity for the former Cincinnati coach, Fickell’s Bearcats upset Notre Dame in 2021 which led them to be the first group of 5 team to reach the Playoff. I’m not saying Wisconsin is definitely a CFP sleeper, but a close game or a win would be a great start to the season and last time Wisconsin played at Lambeau was 10 years ago when they upset No. 5 LSU to start that year en-route to a 10-2 Cotton Bowl season.
3. No. 24 Louisville at No. 9 Ole Miss (Sept. 6. 6:30 pm abc)
After falling a game short of the National Championship in an unexpected feel good run in the Playoff. Pete Golding’s Ole Miss Rebels have a great opportunity to start this season off on the right track. The No. 9 Rebels go to Nissan Stadium in Nashville Tennessee to take on the No. 24 Louisville Cardinals. The Rebels do have key players like QB Trinidad Chambliss and RB Kewan Lacy coming back to help power the offense. Louisville has a chance to get a huge early season signature win, especially being in an ACC conference that is wide open. This one is a good opportunity for these two teams.
4. North Texas at No. 6 Indiana (Sept. 5. 11:00 am FOX)
The world will get their first look at what the post-Fernando Mendoza Indiana Hoosiers will look like. They will also have to get used to the title, “defending champion” before Indiana’s name this year. While I think Indiana will win this game, and know from the head and heart that you should never doubt Head Coach Curt Cignetti, this one could be closer then people might think. In the opener last year vs Old Dominion, Indiana won 27-14 but struggled early in the game as for most of the first quarter until a late TD with 3+ minutes to go it was only a 10-7 Indiana lead. While they lost a lot of the key pieces including their head coach. The Mean Green last season just missed out on a playoff spot by losing to Tulane in the American Championship last season. So it will be interesting to see what Indiana looks like if they’re off and firing early, or having some growing pains.